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Tokyo Metropolitan Assembly
2021-6-9 · 、、などをにのをしています。 コロナウイルス の（378） びにするなおらせ（3531） ...
MODIFIED RELAXIN POLYPEPTIDES AND THEIR USES
2013-9-12 · Modified relaxin polypeptides and their uses thereof are provided. Exemplary embodiments provide relaxin polypeptides which include one or more amino acid substitutions with natural or non-naturally encoded amino acids, and/or linkage to a water-soluble polymer, such as polyethylene glycol.
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Nucleic acids encoding modified relaxin polypeptides ...
2016-9-30 · Kono et al., "Energy minimization method using automata network for sequence and side-chain conformation prediction from given backbone geometry", Proteins (1994) 19(3):244-255. Kourouklis et al., "Programmable ribozymes for mischarging tRNA with nonnatural amino acids and the applications to translation", Methods (2005) 36:239-244.
Regulation of Sterol Synthesis in Eukaryotes | Annual ...
2019-7-17 · Cholesterol is an essential component of mammalian cell membranes and is required for proper membrane permeability, fluidity, organelle identity, and protein function. Cells maintain sterol homeostasis by multiple feedback controls that act through transcriptional and posttranscriptional mechanisms. The membrane-bound transcription factor sterol regulatory element binding protein …
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Advances in Resist Materials and Processing …
2007-3-15 · Author(s): Gregg M. Gallatin; Patrick Naulleau; Robert Brainard Show Abstract Recent experimental results indicate that current resists lack the ability to simultaneously meet the 2005 International Roadmap for Semiconductors (ITRS) goals for Resolution, Line Edge Roughness (LER) and Sensitivity (RLS).
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Whole-genome duplication increases tumor cell …
2016-1-1 · Degenhardt Y, Greshock J, Laquerre S, Gilmartin AG, Jing J, Richter M, Zhang X, Bleam M, Halsey W, Hughes A, Moy C, Liu-Sullivan N, Powers S, Bachman K, Jackson J, Weber B, et al. Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability. Mol Cancer Ther. 2010; 9:2079–2089.
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Neurolastin, a dynamin family GTPase, translocates to ...
Neurolastin is a dynamin family GTPase that also contains a RING domain and exhibits both GTPase and E3 ligase activities. It is specifically expressed in the brain and is important for synaptic transmission, as neurolastin knockout animals have fewer dendritic spines and exhibit a reduction in functional synapses. Our initial study of neurolastin revealed that it is membrane-associated and ...
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Molecular biology and pathogenicity of mycoplasmas ...
1998-12-1 · Because of the wide scope of the review and space limitations, emphasis will be put on the more recent findings, published since 1990. The interested reader is referred to a number of books on various aspects of mycoplasmology published during the last decade or so (210, 277, 365, 370, 395, 459, 473).A wealth of information can be found in the proceedings of the biannual meetings of the ...
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Enzymatic Transition States and Drug Design.
2018-10-18 · Kinetic isotope effects for [1′– 14 C]AMP primary effect and [1′– 3 H]AMP α-secondary effect with different enzyme conditions and compared to the acid-catalyzed solvolysis of AMP in 0.1 M HCl at 50 °C. 21,22 % KIE = (KIE – 1.000).
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Environment sensitive hydrogels for drug delivery ...
2019-11-1 · The special focus on the environment-sensitive hydrogels has facilitated breakthrough advances in drug delivery (e.g., decrease in dose frequency, increase in the duration of release with reduced side effects, ease of preparation and administration) for the better treatment of various pathological conditions.
Toll-pathway in tiger shrimp (Penaeus monodon) …
2014-12-1 · Two key molecules of Toll-pathway – MyD88 and TRAF6 of shrimp, Penaeus monodon were sequenced. Constitutive expression of the genes and PmTLR was observed in 15 different tissues of healthy shrimp.. White spot syndrome virus (WSSV)-infected shrimp showed increased expression of the genes and PmTLR.. Cultured shrimp haemocytes exposed to WSSV and poly I:C showed increased …
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Neuropeptides regulating development and …
2005-6-1 · Abstract. This review deals with those neuropeptidic hormones that are completely known in their primary structure together with the control processes that are linked directly or indirectly to development and reproduction. Actions are assessed for neuropeptides that regulate ecdysteroid and Juvenile Hormone production; oocyte growth or yolk deposition; and ecdysis and courtship behaviour. …
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